Staple과 수종의 봉합물의 봉합부위 창상치유 조직 반응
Tissue healing response of incised wound sutured by staples and various suture materials
서민정, 윤성탁,
소속 상세정보
서민정 ( ) - 단국대학교 농과대학 축산학과
윤성탁 ( ) - 단국대학교
KMID : 0360119960180030500
Abstract
The purpose of this study was to observe the tissue response in applying staples and various suture materials to both scalp and buccal mucosa in rabbits. 18 rabbits were divided into 6 groups. The incised wounds of both scalp and buccal mucosa
were
sutured with staples, polyglactin 910, chromic catgut, mer silk and nylon.
The experimental animals were sacrificed after 1, 3, 5, 7, 10, 14 days posto peratively 3 animals at one time. The tissue was stained with Hematoxylin and eosin, and Masson's Trichrom.
In light microscopic examinations, the sutured sites were examined histologic cally according to 6 degrees about inflammation and collagen deposit.
@ES The results were obtained as follows,
@EN 1. The chromic catgut, and absorbable suture material, was absorbed by 7 days, whereas polyglactin 919 and mersilk began to get absorbed after 7 days.
2. Mersilk manifested a broad range of inflammation in the scalp, and both staple and nylon showed a severe inflammatory reaction in the buccal mucosa.
3. With polyglactin 910, both tissue samples showed only minor foreign body reaction, however in the scalp, the process of fibrosis took place compara tively slowly, whereas in the buccal mucosa, it occurred promptly and manifested active
fibrosis
by 7
days.
4. Mersilk showed widespread a matrix formation in both scalp and buccal mucosa, and showed the most severe inflammatory reaction by 3 days, which did not seem to decrease even after 7 days.
5. Both staple and nylon showed relatively a severe inflammatory reaction, however fibrosis took place rather promptly compared to the other groups.
6. Generally, in the buccal mucosa fibrosis occurred more promptly-than in the scalp in both control and experimental groups.
7. Retention of the suture material and stability of the knot were the best with the staple, and better stability was manifested by the multi-stranded poly glactin 910 and mersilk than singlestranded chromic catgut and nylon.
From above results, in the buccal mucosa absorbable suture materials especially polyglactin 910 showed better response in the aspect of inflammatory reaction, while in the scalp monofilament suture materials such as staple and nylon manifested a
early
fibrosis and collagen formation.
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